Cardiac Metabolism and Arrhythmias

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Cardiac metabolism and arrhythmias.

Sudden cardiac death remains a leading cause of death in the Western world, accounting for up to 20% of all deaths in the United States1,2 The major causes of sudden cardiac death in adults age 35 and older are coronary artery disease (70% to 80%) and dilated cardiomyopathy (10% to 15%).3 At the molecular level, a wide variety of mechanisms contribute to arrhythmias that cause sudden cardiac de...

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Basic Science for the Clinical Electrophysiologist Cardiac Metabolism and Arrhythmias

Sudden cardiac death remains a leading cause of death in the Western world, accounting for up to 20% of all deaths in the United States1,2 The major causes of sudden cardiac death in adults age 35 and older are coronary artery disease (70% to 80%) and dilated cardiomyopathy (10% to 15%).3 At the molecular level, a wide variety of mechanisms contribute to arrhythmias that cause sudden cardiac de...

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Cardiac Rhythms and Arrhythmias

node as the region responsible for activation of the heart.1 Laslett first suggested sinus node dysfunction as a cause of bradycardia in 1909, and during the 1950s and 1960s Short, Ferrer, Lown, and others described the clinical spectrum of sinus node dysfunction that is commonly called the “sick sinus syndrome resting sinus bradycardia.”2-5 Sinus node dysfunction can have multiple electrocardi...

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Stress and Cardiac Arrhythmias

Stress can exert adverse effect on cardiovascular health. Psychosocial stress adversely affects the autonomic homeostasis. This in turn can result in metabolic abnormalities, inflammation and dysfunction of endothelium [1]. Changes in the autonomic homeostasis can be a major trigger for ventricular tachyarrhythmias [2]. Increased sympathetic nervous activity can cause increased proarrhythmic re...

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Cardiac arrhythmias and pacing.

Clinical trials. In the last two years, a number of landmark clinical trials have been published which further our understanding and clinical management of patients with atrial fibrillation (AF). Two of the major goals in the treatment of this condition include reducing progression or recurrence of the arrhythmia and decreasing the risk of cardiovascular events, thereby improving quality of lif...

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ژورنال

عنوان ژورنال: Circulation: Arrhythmia and Electrophysiology

سال: 2009

ISSN: 1941-3149,1941-3084

DOI: 10.1161/circep.108.817320